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Mutant B-RAF Regulates a Rac-dependent Cadherin Switch in Melanoma
The ability of cells to invade into the dermis is a critical event in the development of cutaneous melanoma and ultimately an indicator of poor prognosis. However, the molecular events surrounding the acquisition of this invasive phenotype remain incompletely understood. Mutations in B-RAF are frequ...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021488/ https://www.ncbi.nlm.nih.gov/pubmed/23208503 http://dx.doi.org/10.1038/onc.2012.492 |