Integrity of the LXXLL motif in Stat6 is required for the inhibition of breast cancer cell growth and enhancement of differentiation in the context of progesterone

BACKGROUND: Progesterone is essential for the proliferation and differentiation of mammary gland epithelium. Studies of breast cancer cells have demonstrated a biphasic progesterone response consisting of an initial proliferative burst followed by sustained growth arrest. However, the transcriptiona...

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Detalles Bibliográficos
Autores principales: Wei, Min, He, Qi, Yang, Zhongyin, Wang, Zhiwei, Zhang, Qing, Liu, Bingya, Gu, Qinlong, Su, Liping, Yu, Yingyan, Zhu, Zhenggang, Zhang, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021501/
https://www.ncbi.nlm.nih.gov/pubmed/24401087
http://dx.doi.org/10.1186/1471-2407-14-10

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