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Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells

BACKGROUND: Transforming growth factor-beta (TGF-β) induces the epithelial-to-mesenchymal transition (EMT) leading to increased cell plasticity at the onset of cancer cell invasion and metastasis. Mechanisms involved in TGF-β-mediated EMT and cell motility are unclear. Recent studies showed that p53...

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Detalles Bibliográficos
Autores principales:	Boudreau, H E, Casterline, B W, Burke, D J, Leto, T L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021516/ https://www.ncbi.nlm.nih.gov/pubmed/24714748 http://dx.doi.org/10.1038/bjc.2014.165

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