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Potent anti-tumour activity of a novel conditionally replicating adenovirus for melanoma via inhibition of migration and invasion

BACKGROUND: Conditionally replicating adenoviruses (CRAds) represent a novel class of oncological therapeutic agents. One strategy to ensure tumour targeting is to place the essential viral genes under the control of tumour-specific promoters. Ki67 has been selected as a cancer gene therapy target,...

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Detalles Bibliográficos
Autores principales:	Jiang, G, Yang, C-S, Xu, D, Sun, C, Zheng, J-N, Lei, T-C, Liu, Y-Q
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021521/ https://www.ncbi.nlm.nih.gov/pubmed/24714752 http://dx.doi.org/10.1038/bjc.2014.177

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