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N-nitroso-N-ethylurea activates DNA damage surveillance pathways and induces transformation in mammalian cells

BACKGROUND: The DNA damage checkpoint signalling cascade sense damaged DNA and coordinates cell cycle arrest, DNA repair, and/or apoptosis. However, it is still not well understood how the signalling system differentiates between different kinds of DNA damage. N-nitroso-N-ethylurea (NEU), a DNA ethy...

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Detalles Bibliográficos
Autores principales:	Bodakuntla, Satish, V, Libi Anandi, Sural, Surojit, Trivedi, Prasad, Lahiri, Mayurika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021545/ https://www.ncbi.nlm.nih.gov/pubmed/24758542 http://dx.doi.org/10.1186/1471-2407-14-287

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