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Ganglioside GD2 in reception and transduction of cell death signal in tumor cells

BACKGROUND: Ganglioside GD2 is expressed on plasma membranes of various types of malignant cells. One of the most promising approaches for cancer immunotherapy is the treatment with monoclonal antibodies recognizing tumor-associated markers such as ganglioside GD2. It is considered that major mechan...

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Detalles Bibliográficos
Autores principales: Doronin, Igor I, Vishnyakova, Polina A, Kholodenko, Irina V, Ponomarev, Eugene D, Ryazantsev, Dmitry Y, Molotkovskaya, Irina M, Kholodenko, Roman V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021548/
https://www.ncbi.nlm.nih.gov/pubmed/24773917
http://dx.doi.org/10.1186/1471-2407-14-295