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CopyRighter: a rapid tool for improving the accuracy of microbial community profiles through lineage-specific gene copy number correction
BACKGROUND: Culture-independent molecular surveys targeting conserved marker genes, most notably 16S rRNA, to assess microbial diversity remain semi-quantitative due to variations in the number of gene copies between species. RESULTS: Based on 2,900 sequenced reference genomes, we show that 16S rRNA...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021573/ https://www.ncbi.nlm.nih.gov/pubmed/24708850 http://dx.doi.org/10.1186/2049-2618-2-11 |