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Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies
BACKGROUND: Mitochondria play a critical role in the cell and have DNA independent of the nuclear genome. There is much evidence that mitochondrial DNA (mtDNA) variation plays a role in human health and disease, however, this area of investigation has lagged behind research into the role of nuclear...
Autores principales: | Mitchell, Sabrina L, Hall, Jacob B, Goodloe, Robert J, Boston, Jonathan, Farber-Eger, Eric, Pendergrass, Sarah A, Bush, William S, Crawford, Dana C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021623/ https://www.ncbi.nlm.nih.gov/pubmed/24731735 http://dx.doi.org/10.1186/1756-0381-7-6 |
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