Cargando…
Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis
BACKGROUND: Myocardial fibrosis is a pathological process that is characterized by disrupted regulation of extracellular matrix proteins resulting in permanent scarring of the heart tissue and eventual diastolic heart failure. Pro-fibrotic molecules including transforming growth factor-β and connect...
Autores principales: | Rosin, Nicole L, Gareau, Alison J, Betsch, Devin, Falkenham, Alec, Sopel, Mryanda J, Lee, Timothy DG, Légaré, Jean-Francois |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021636/ https://www.ncbi.nlm.nih.gov/pubmed/24721281 http://dx.doi.org/10.1186/1755-1536-7-6 |
Ejemplares similares
-
Treatment with Activated Protein C (aPC) Is Protective during the Development of Myocardial Fibrosis: An Angiotensin II Infusion Model in Mice
por: Sopel, Mryanda J., et al.
Publicado: (2012) -
Connective tissue growth factor expression after angiotensin II exposure is dependent on transforming growth factor-β signaling via the canonical Smad-dependent pathway in hypertensive induced myocardial fibrosis
por: Wong, Chloe Kok Sum, et al.
Publicado: (2018) -
AngiotensinII Preconditioning Promotes Angiogenesis In Vitro via ERKs Phosphorylation
por: Guan, Aili, et al.
Publicado: (2012) -
Activation of Yes-Associated Protein/PDZ-Binding Motif Pathway Contributes to Endothelial Dysfunction and Vascular Inflammation in AngiotensinII Hypertension
por: Xu, Qian, et al.
Publicado: (2021) -
Recovery free of heart failure after acute coronary syndrome and coronary revascularization
por: Falkenham, Alec, et al.
Publicado: (2017)