Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients

BACKGROUND: Alpha fetoprotein (AFP) is an oncofetal antigen over-expressed by many hepatocellular cancers (HCC). We previously demonstrated that HLA-A2-restricted epitopes derived from AFP are immunogenic in vitro and in vivo despite high circulating levels of this oncofetal antigen. In order to tes...

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Detalles Bibliográficos
Autores principales: Butterfield, Lisa H, Economou, James S, Gamblin, T Clark, Geller, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021640/
https://www.ncbi.nlm.nih.gov/pubmed/24708667
http://dx.doi.org/10.1186/1479-5876-12-86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021640/
https://www.ncbi.nlm.nih.gov/pubmed/24708667
http://dx.doi.org/10.1186/1479-5876-12-86

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