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Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients

BACKGROUND: Alpha fetoprotein (AFP) is an oncofetal antigen over-expressed by many hepatocellular cancers (HCC). We previously demonstrated that HLA-A2-restricted epitopes derived from AFP are immunogenic in vitro and in vivo despite high circulating levels of this oncofetal antigen. In order to tes...

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Detalles Bibliográficos
Autores principales:	Butterfield, Lisa H, Economou, James S, Gamblin, T Clark, Geller, David A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021640/ https://www.ncbi.nlm.nih.gov/pubmed/24708667 http://dx.doi.org/10.1186/1479-5876-12-86

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