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Active Smoking Increases Microsomal PGE(2)-Synthase-1/PGE-Receptor-4 Axis in Human Abdominal Aortic Aneurysms

Background. The cyclooxygenase- (COX-) 2/microsomal PGE-synthase- (mPGES-) 1/PGE-receptor- (EP-) 4 axis could play a key role in the physiopathology of abdominal aortic aneurysm (AAA) in humans. In this study, we investigated the influence of cardiovascular risk factors on the expression of the PGE(...

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Detalles Bibliográficos
Autores principales: Dilmé, Jaime-Félix, Solà-Villà, David, Bellmunt, Sergi, Romero, José-María, Escudero, José-Román, Camacho, Mercedes, Vila, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021751/
https://www.ncbi.nlm.nih.gov/pubmed/24876670
http://dx.doi.org/10.1155/2014/316150