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BRAFV600E immunohistochemistry in conjunction with mismatch repair status predicts survival in patients with colorectal cancer
Immunohistochemistry has recently been validated for the detection of the BRAFV600E mutation across a range of tumor types. In colorectal carcinoma, the presence of the BRAFV600E mutation can be used to virtually exclude Lynch syndrome in mismatch repair-deficient tumors. In mismatch repair-proficie...
Autores principales: | Toon, Christopher W, Chou, Angela, DeSilva, Keshani, Chan, Joseph, Patterson, Jillian, Clarkson, Adele, Sioson, Loretta, Jankova, Lucy, Gill, Anthony J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021849/ https://www.ncbi.nlm.nih.gov/pubmed/24157612 http://dx.doi.org/10.1038/modpathol.2013.200 |
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