A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration

Management of intestinal failure remains a clinical challenge and total parenteral nutrition, intestinal elongation and/or transplantation are partial solutions. In this study, using a detergent-enzymatic treatment (DET), we optimize in rats a new protocol that creates a natural intestinal scaffold,...

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Detalles Bibliográficos
Autores principales: Totonelli, Giorgia, Maghsoudlou, Panagiotis, Garriboli, Massimo, Riegler, Johannes, Orlando, Giuseppe, Burns, Alan J., Sebire, Neil J., Smith, Virpi V., Fishman, Jonathan M., Ghionzoli, Marco, Turmaine, Mark, Birchall, Martin A., Atala, Anthony, Soker, Shay, Lythgoe, Mark F., Seifalian, Alexander, Pierro, Agostino, Eaton, Simon, De Coppi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022101/
https://www.ncbi.nlm.nih.gov/pubmed/22305104
http://dx.doi.org/10.1016/j.biomaterials.2012.01.012

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