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Global transcript and phenotypic analysis of yeast cells expressing Ssa1, Ssa2, Ssa3 or Ssa4 as sole source of cytosolic Hsp70-Ssa chaperone activity
BACKGROUND: Cytosolic Hsp70 is a ubiquitous molecular chaperone that is involved in responding to a variety of cellular stresses. A major function of Hsp70 is to prevent the aggregation of denatured proteins by binding to exposed hydrophobic regions and preventing the accumulation of amorphous aggre...
Autores principales: | Hasin, Naushaba, Cusack, Sarah A, Ali, Shahin S, Fitzpatrick, David A, Jones, Gary W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022180/ https://www.ncbi.nlm.nih.gov/pubmed/24628813 http://dx.doi.org/10.1186/1471-2164-15-194 |
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