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Non-stationary (13)C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation

BACKGROUND: Mapping the intracellular fluxes for established mammalian cell lines becomes increasingly important for scientific and economic reasons. However, this is being hampered by the high complexity of metabolic networks, particularly concerning compartmentation. RESULTS: Intracellular fluxes...

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Detalles Bibliográficos
Autores principales:	Nicolae, Averina, Wahrheit, Judith, Bahnemann, Janina, Zeng, An-Ping, Heinzle, Elmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022241/ https://www.ncbi.nlm.nih.gov/pubmed/24773761 http://dx.doi.org/10.1186/1752-0509-8-50

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