Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy

Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy ana...

Descripción completa

Detalles Bibliográficos
Autores principales: Malaguarnera, Giulia, Gagliano, Caterina, Giordano, Maria, Salomone, Salvatore, Vacante, Marco, Bucolo, Claudio, Caraci, Filippo, Reibaldi, Michele, Drago, Filippo, Avitabile, Teresio, Motta, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022262/
https://www.ncbi.nlm.nih.gov/pubmed/24877066
http://dx.doi.org/10.1155/2014/191497
_version_ 1782316372499365888
author Malaguarnera, Giulia
Gagliano, Caterina
Giordano, Maria
Salomone, Salvatore
Vacante, Marco
Bucolo, Claudio
Caraci, Filippo
Reibaldi, Michele
Drago, Filippo
Avitabile, Teresio
Motta, Massimo
author_facet Malaguarnera, Giulia
Gagliano, Caterina
Giordano, Maria
Salomone, Salvatore
Vacante, Marco
Bucolo, Claudio
Caraci, Filippo
Reibaldi, Michele
Drago, Filippo
Avitabile, Teresio
Motta, Massimo
author_sort Malaguarnera, Giulia
collection PubMed
description Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy analyzing the plasma levels of homocysteine in 63 diabetic type 2 patients with nonproliferative retinopathy (NPDR), 62 patients with proliferative diabetic retinopathy (PDR), 50 healthy subjects used as control group, and 75 randomly selected patients.
format Online
Article
Text
id pubmed-4022262
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-40222622014-05-29 Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy Malaguarnera, Giulia Gagliano, Caterina Giordano, Maria Salomone, Salvatore Vacante, Marco Bucolo, Claudio Caraci, Filippo Reibaldi, Michele Drago, Filippo Avitabile, Teresio Motta, Massimo Biomed Res Int Research Article Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy analyzing the plasma levels of homocysteine in 63 diabetic type 2 patients with nonproliferative retinopathy (NPDR), 62 patients with proliferative diabetic retinopathy (PDR), 50 healthy subjects used as control group, and 75 randomly selected patients. Hindawi Publishing Corporation 2014 2014-04-28 /pmc/articles/PMC4022262/ /pubmed/24877066 http://dx.doi.org/10.1155/2014/191497 Text en Copyright © 2014 Giulia Malaguarnera et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Malaguarnera, Giulia
Gagliano, Caterina
Giordano, Maria
Salomone, Salvatore
Vacante, Marco
Bucolo, Claudio
Caraci, Filippo
Reibaldi, Michele
Drago, Filippo
Avitabile, Teresio
Motta, Massimo
Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy
title Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy
title_full Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy
title_fullStr Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy
title_full_unstemmed Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy
title_short Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy
title_sort homocysteine serum levels in diabetic patients with non proliferative, proliferative and without retinopathy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022262/
https://www.ncbi.nlm.nih.gov/pubmed/24877066
http://dx.doi.org/10.1155/2014/191497
work_keys_str_mv AT malaguarneragiulia homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT gaglianocaterina homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT giordanomaria homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT salomonesalvatore homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT vacantemarco homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT bucoloclaudio homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT caracifilippo homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT reibaldimichele homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT dragofilippo homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT avitabileteresio homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy
AT mottamassimo homocysteineserumlevelsindiabeticpatientswithnonproliferativeproliferativeandwithoutretinopathy

Ejemplares similares