Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum

BACKGROUND: Pseudoxanthoma elasticum (PXE) is characterized by skin (papular lesions), ocular (subretinal neovascularisation) and cardiovascular manifestations (peripheral artery disease), due to mineralization and fragmentation of elastic fibres in the extracellular matrix (ECM). Caused by mutation...

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Detalles Bibliográficos
Autores principales: Hosen, Mohammad J, Coucke, Paul J, Le Saux, Olivier, De Paepe, Anne, Vanakker, Olivier M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022264/
https://www.ncbi.nlm.nih.gov/pubmed/24775865
http://dx.doi.org/10.1186/1750-1172-9-66

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