Cargando…

Accumulation of Misfolded SOD1 in Dorsal Root Ganglion Degenerating Proprioceptive Sensory Neurons of Transgenic Mice with Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is an adult-onset progressive neurodegenerative disease affecting upper and lower motoneurons (MNs). Although the motor phenotype is a hallmark for ALS, there is increasing evidence that systems other than the efferent MN system can be involved. Mutations of super...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sábado, Javier, Casanovas, Anna, Tarabal, Olga, Hereu, Marta, Piedrafita, Lídia, Calderó, Jordi, Esquerda, Josep E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022303/ https://www.ncbi.nlm.nih.gov/pubmed/24877142 http://dx.doi.org/10.1155/2014/852163

Ejemplares similares

Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis
por: Salvany, Sara, et al.
Publicado: (2022)

Microglial recruitment and mechanisms involved in the disruption of afferent synaptic terminals on spinal cord motor neurons after acute peripheral nerve injury
por: Salvany, Sara, et al.
Publicado: (2021)

Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury
por: Casanovas, Anna, et al.
Publicado: (2017)

Persistent NRG1 Type III Overexpression in Spinal Motor Neurons Has No Therapeutic Effect on ALS-Related Pathology in SOD1(G93A) Mice
por: Hernández, Sara, et al.
Publicado: (2023)

The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons
por: Gatius, Alaó, et al.
Publicado: (2020)

Motoneuron deafferentation and gliosis occur in association with neuromuscular regressive changes during ageing in mice
por: Blasco, Alba, et al.
Publicado: (2020)

Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system
por: Gras, Sílvia, et al.
Publicado: (2021)

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis
por: Paré, Bastien, et al.
Publicado: (2018)

Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice
por: Wu, Haohao, et al.
Publicado: (2021)

Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNΔ7 mouse model of SMA
por: Narcís, J. Oriol, et al.
Publicado: (2018)

Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis
por: Pokrishevsky, Edward, et al.
Publicado: (2012)

Adherent Monomer-Misfolded SOD1
por: Watanabe, Yasuhiro, et al.
Publicado: (2008)

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1
por: Pickles, Sarah, et al.
Publicado: (2013)

Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons
por: Kumar, Meenakshi Sundaram, et al.
Publicado: (2022)

Early upregulation of cytosolic phospholipase A(2)α in motor neurons is induced by misfolded SOD1 in a mouse model of amyotrophic lateral sclerosis
por: Malada Edelstein, Yafa Fetfet, et al.
Publicado: (2021)

In vitro modelling of human proprioceptive sensory neurons in the neuromuscular system
por: Badiola-Mateos, Maider, et al.
Publicado: (2022)

An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis
por: Rotunno, Melissa S., et al.
Publicado: (2013)

ALS-linked misfolded SOD1 species have divergent impacts on mitochondria
por: Pickles, Sarah, et al.
Publicado: (2016)

Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways
por: Sekhar, Ashok, et al.
Publicado: (2015)

Misfolding at the synapse: A role in amyotrophic lateral sclerosis pathogenesis?
por: Lum, Jeremy S., et al.
Publicado: (2022)

Features of wild-type human SOD1 limit interactions with misfolded aggregates of mouse G86R Sod1
por: Qualls, David A, et al.
Publicado: (2013)

Partially native intermediates mediate misfolding of SOD1 in single-molecule folding trajectories
por: Sen Mojumdar, Supratik, et al.
Publicado: (2017)

Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology
por: Pace, Michael C., et al.
Publicado: (2018)

Mapping of the Sensory Innervation of the Mouse Lung by Specific Vagal and Dorsal Root Ganglion Neuronal Subsets
por: Kim, Seol-Hee, et al.
Publicado: (2022)

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis
por: Prasad, Archana, et al.
Publicado: (2019)

Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis
por: McAlary, Luke, et al.
Publicado: (2019)

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis
por: Lee, John D, et al.
Publicado: (2013)

Comparative Magnetic Resonance Imaging and Histopathological Correlates in Two SOD1 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis
por: Caron, Ilaria, et al.
Publicado: (2015)

Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
por: Yan, Lina, et al.
Publicado: (2018)

Retinal Ganglion Cell Loss and Microglial Activation in a SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
por: Rojas, Pilar, et al.
Publicado: (2021)

Gate control of sensory neurotransmission in peripheral ganglia by proprioceptive sensory neurons
por: Fuller, Alice M, et al.
Publicado: (2023)

SOD1 and Amyotrophic Lateral Sclerosis: Mutations and Oligomerization
por: Banci, Lucia, et al.
Publicado: (2008)

Metal-deficient SOD1 in amyotrophic lateral sclerosis
por: Hilton, James B., et al.
Publicado: (2015)

Light-evoked Somatosensory Perception of Transgenic Rats That Express Channelrhodopsin-2 in Dorsal Root Ganglion Cells
por: Ji, Zhi-Gang, et al.
Publicado: (2012)

MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS
por: Shvil, Neta, et al.
Publicado: (2018)

Expression and properties of hyperpolarization-activated current in rat dorsal root ganglion neurons with known sensory function
por: Gao, L L, et al.
Publicado: (2012)

Rosmarinic Acid Alleviates Neurological Symptoms in the G93A-SOD1 Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
por: Seo, Ji-Seon, et al.
Publicado: (2015)

Corrigendum: Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis
por: McAlary, Luke, et al.
Publicado: (2020)

Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
por: Saccon, Rachele A., et al.
Publicado: (2013)

Optimised and Rapid Pre-clinical Screening in the SOD1(G93A) Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
por: Mead, Richard J., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_f43e22bvup0act66hkl46as194