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Bortezomib Treatment Produces Nocifensive Behavior and Changes in the Expression of TRPV1, CGRP, and Substance P in the Rat DRG, Spinal Cord, and Sciatic Nerve
To investigate neurochemical changes associated with bortezomib-induced painful peripheral neuropathy (PN), we examined the effects of a single-dose intravenous administration of bortezomib and a well-established “chronic” schedule in a rat model of bortezomib-induced PN. The TRPV1 channel and senso...
Autores principales: | Quartu, M., Carozzi, V. A., Dorsey, S. G., Serra, M. P., Poddighe, L., Picci, C., Boi, M., Melis, T., Del Fiacco, M., Meregalli, C., Chiorazzi, A., Renn, C. L., Cavaletti, G., Marmiroli, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022313/ https://www.ncbi.nlm.nih.gov/pubmed/24877063 http://dx.doi.org/10.1155/2014/180428 |
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