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WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells
BACKGROUND: Wnt proteins are important for developmental processes and certain diseases. WNT5A is a non-canonical Wnt protein that previously has been shown to play a role in the progression of malignant melanoma. High expression of WNT5A in melanoma tumors correlates to formation of distant metasta...
Autores principales: | Ekström, Elin J, Bergenfelz, Caroline, von Bülow, Verena, Serifler, Filiz, Carlemalm, Eric, Jönsson, Göran, Andersson, Tommy, Leandersson, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022450/ https://www.ncbi.nlm.nih.gov/pubmed/24766647 http://dx.doi.org/10.1186/1476-4598-13-88 |
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