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In-Vivo Real-Time Control of Protein Expression from Endogenous and Synthetic Gene Networks
We describe an innovative experimental and computational approach to control the expression of a protein in a population of yeast cells. We designed a simple control algorithm to automatically regulate the administration of inducer molecules to the cells by comparing the actual protein expression le...
Autores principales: | Menolascina, Filippo, Fiore, Gianfranco, Orabona, Emanuele, De Stefano, Luca, Ferry, Mike, Hasty, Jeff, di Bernardo, Mario, di Bernardo, Diego |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022480/ https://www.ncbi.nlm.nih.gov/pubmed/24831205 http://dx.doi.org/10.1371/journal.pcbi.1003625 |
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