slanDCs in carcinoma-draining lymph nodes

Dendritic cells (DCs) are known to initiate adaptive immune responses against malignant cells. However, the role in anticancer immunosurveillance of 6-sulfo LacNAc-expressing DCs (slanDCs), a distinct population of circulating and tissue-resident pro-inflammatory DCs, is unclear. We have recently de...

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Detalles Bibliográficos
Autores principales: Vermi, William, Lonardi, Silvia, Bugatti, Mattia, Calzetti, Federica, Micheletti, Alessandra, Cassatella, Marco A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022602/
https://www.ncbi.nlm.nih.gov/pubmed/24843832
http://dx.doi.org/10.4161/onci.28246
Descripción
Sumario:Dendritic cells (DCs) are known to initiate adaptive immune responses against malignant cells. However, the role in anticancer immunosurveillance of 6-sulfo LacNAc-expressing DCs (slanDCs), a distinct population of circulating and tissue-resident pro-inflammatory DCs, is unclear. We have recently demonstrated the involvement of slanDCs in nodal immune responses against carcinoma cells.

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