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Novel effects of Brefeldin A (BFA) in signaling through the insulin receptor (IR) pathway and regulating FoxO1-mediated transcription

Brefeldin A (BFA) is a fungal metabolite best known for its ability to inhibit activation of ADP-ribosylation factor (Arf) and thereby inhibit secretory traffic. BFA also appears to regulate the trafficking of the GLUT4 glucose transporter by inducing its relocation from intracellular stores to the...

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Detalles Bibliográficos
Autores principales: Wyrozumska, Paulina, Ashley, Jason W, Ramanadham, Sasanka, Liu, Qinglan, Garvey, W Timothy, Sztul, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022606/
https://www.ncbi.nlm.nih.gov/pubmed/24843827
http://dx.doi.org/10.4161/cl.27732