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Novel effects of Brefeldin A (BFA) in signaling through the insulin receptor (IR) pathway and regulating FoxO1-mediated transcription
Brefeldin A (BFA) is a fungal metabolite best known for its ability to inhibit activation of ADP-ribosylation factor (Arf) and thereby inhibit secretory traffic. BFA also appears to regulate the trafficking of the GLUT4 glucose transporter by inducing its relocation from intracellular stores to the...
Autores principales: | Wyrozumska, Paulina, Ashley, Jason W, Ramanadham, Sasanka, Liu, Qinglan, Garvey, W Timothy, Sztul, Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022606/ https://www.ncbi.nlm.nih.gov/pubmed/24843827 http://dx.doi.org/10.4161/cl.27732 |
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