Cargando…

Novel effects of Brefeldin A (BFA) in signaling through the insulin receptor (IR) pathway and regulating FoxO1-mediated transcription

Brefeldin A (BFA) is a fungal metabolite best known for its ability to inhibit activation of ADP-ribosylation factor (Arf) and thereby inhibit secretory traffic. BFA also appears to regulate the trafficking of the GLUT4 glucose transporter by inducing its relocation from intracellular stores to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Wyrozumska, Paulina, Ashley, Jason W, Ramanadham, Sasanka, Liu, Qinglan, Garvey, W Timothy, Sztul, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022606/
https://www.ncbi.nlm.nih.gov/pubmed/24843827
http://dx.doi.org/10.4161/cl.27732

Ejemplares similares