Serum Stability and Physicochemical Characterization of a Novel Amphipathic Peptide C6M1 for SiRNA Delivery

The efficient delivery of nucleic acids as therapeutic agents is a major challenge in gene therapy. Peptides have recently emerged as a novel carrier for delivery of drugs and genes. C6M1 is a designed amphipathic peptide with the ability to form stable complexes with short interfering RNA (siRNA)....

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Detalles Bibliográficos
Autores principales: Jafari, Mousa, Xu, Wen, Pan, Ran, Sweeting, Chad M., Karunaratne, Desiree Nedra, Chen, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022676/
https://www.ncbi.nlm.nih.gov/pubmed/24831131
http://dx.doi.org/10.1371/journal.pone.0097797

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