The Apical Junctional Complex in Respiratory Diseases

The epithelium, including the respiratory system, acts as a selective gate between the outside environment and underlying tissue. Epithelial cells are polarized due to the formation of the apical junctional complex, which includes adherent junctions and tight junctions. Endothelial cells are one of...

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Detalles Bibliográficos
Autor principal: Jang, An-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chonnam National University Medical School 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022791/
https://www.ncbi.nlm.nih.gov/pubmed/24855600
http://dx.doi.org/10.4068/cmj.2014.50.1.1
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author Jang, An-Soo
author_facet Jang, An-Soo
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description The epithelium, including the respiratory system, acts as a selective gate between the outside environment and underlying tissue. Epithelial cells are polarized due to the formation of the apical junctional complex, which includes adherent junctions and tight junctions. Endothelial cells are one of the most important cellular constituents of blood vessels. Endothelial junctional proteins play important roles in tissue integrity as well as in vascular permeability, leukocyte extravasation, and angiogenesis. This review focuses on the apical junctional complex in respiratory diseases.
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spelling pubmed-40227912014-05-22 The Apical Junctional Complex in Respiratory Diseases Jang, An-Soo Chonnam Med J Review Article The epithelium, including the respiratory system, acts as a selective gate between the outside environment and underlying tissue. Epithelial cells are polarized due to the formation of the apical junctional complex, which includes adherent junctions and tight junctions. Endothelial cells are one of the most important cellular constituents of blood vessels. Endothelial junctional proteins play important roles in tissue integrity as well as in vascular permeability, leukocyte extravasation, and angiogenesis. This review focuses on the apical junctional complex in respiratory diseases. Chonnam National University Medical School 2014-04 2014-04-22 /pmc/articles/PMC4022791/ /pubmed/24855600 http://dx.doi.org/10.4068/cmj.2014.50.1.1 Text en © Chonnam Medical Journal, 2014 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Jang, An-Soo
The Apical Junctional Complex in Respiratory Diseases
title The Apical Junctional Complex in Respiratory Diseases
title_full The Apical Junctional Complex in Respiratory Diseases
title_fullStr The Apical Junctional Complex in Respiratory Diseases
title_full_unstemmed The Apical Junctional Complex in Respiratory Diseases
title_short The Apical Junctional Complex in Respiratory Diseases
title_sort apical junctional complex in respiratory diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022791/
https://www.ncbi.nlm.nih.gov/pubmed/24855600
http://dx.doi.org/10.4068/cmj.2014.50.1.1
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