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A Two-Tier Golgi-Based Control of Organelle Size Underpins the Functional Plasticity of Endothelial Cells

Weibel-Palade bodies (WPBs), endothelial-specific secretory granules that are central to primary hemostasis and inflammation, occur in dimensions ranging between 0.5 and 5 μm. How their size is determined and whether it has a functional relevance are at present unknown. Here, we provide evidence for...

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Detalles Bibliográficos
Autores principales: Ferraro, Francesco, Kriston-Vizi, Janos, Metcalf, Daniel J., Martin-Martin, Belen, Freeman, Jamie, Burden, Jemima J., Westmoreland, David, Dyer, Clare E., Knight, Alex E., Ketteler, Robin, Cutler, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022834/
https://www.ncbi.nlm.nih.gov/pubmed/24794632
http://dx.doi.org/10.1016/j.devcel.2014.03.021