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The phosphorylation of endogenous Nedd4-2 In Na(+)—absorbing human airway epithelial cells

Neural precursor cell expressed, developmentally down-regulated protein 4-2 (Nedd4-2) mediates the internalisation / degradation of epithelial Na(+) channel subunits (α-, β- and γ-ENaC). Serum / glucocorticoid inducible kinase 1 (SGK1) and protein kinase A (PKA) both appear to inhibit this process b...

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Detalles Bibliográficos
Autores principales:	Ismail, Noor A.S., Baines, Deborah L., Wilson, Stuart M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2014
Materias:	Molecular and Cellular Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022840/ https://www.ncbi.nlm.nih.gov/pubmed/24657276 http://dx.doi.org/10.1016/j.ejphar.2014.03.005

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