The RNA-binding Protein TDP-43 Selectively Disrupts MicroRNA-1/206 Incorporation into the RNA-induced Silencing Complex

MicroRNA (miRNA) maturation is regulated by interaction of particular miRNA precursors with specific RNA-binding proteins. Following their biogenesis, mature miRNAs are incorporated into the RNA-induced silencing complex (RISC) where they interact with mRNAs to negatively regulate protein production...

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Detalles Bibliográficos
Autores principales: King, Isabelle N., Yartseva, Valeria, Salas, Donaldo, Kumar, Abhishek, Heidersbach, Amy, Ando, D. Michael, Stallings, Nancy R., Elliott, Jeffrey L., Srivastava, Deepak, Ivey, Kathryn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Gene Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022891/
https://www.ncbi.nlm.nih.gov/pubmed/24719334
http://dx.doi.org/10.1074/jbc.M114.561902

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