Cargando…
Poly (ADP-ribose) polymerase inhibitor: an evolving paradigm in the treatment of prostate cancer
Recent phase I studies have reported single-agent activities of poly (ADP-ribose) polymerase (PARP) inhibitor in sporadic and in BRCA-mutant prostate cancers. Two of the most common genetic alterations in prostate cancer, ETS gene rearrangement and loss of PTEN, have been linked to increased sensiti...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023365/ https://www.ncbi.nlm.nih.gov/pubmed/24589464 http://dx.doi.org/10.4103/1008-682X.123684 |