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The three most important things about origins: location, location, location

The reasons why some DNA replication origins fire earlier than others have remained elusive. New work by Gindin et al suggests that the distribution of replication origins, not their timing per se, is the major determinant of the timing of genome replication in human cells.

Detalles Bibliográficos
Autor principal: Rhind, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023393/
https://www.ncbi.nlm.nih.gov/pubmed/24705498
http://dx.doi.org/10.1002/msb.145202
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description The reasons why some DNA replication origins fire earlier than others have remained elusive. New work by Gindin et al suggests that the distribution of replication origins, not their timing per se, is the major determinant of the timing of genome replication in human cells.
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spelling pubmed-40233932014-05-16 The three most important things about origins: location, location, location Rhind, Nicholas Mol Syst Biol News & Views The reasons why some DNA replication origins fire earlier than others have remained elusive. New work by Gindin et al suggests that the distribution of replication origins, not their timing per se, is the major determinant of the timing of genome replication in human cells. European Molecular Biology Organization 2014-04-04 /pmc/articles/PMC4023393/ /pubmed/24705498 http://dx.doi.org/10.1002/msb.145202 Text en © 2014 EMBO This is an open access article under the terms of the Creative Commons Attribution 4.0 (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle News & Views
Rhind, Nicholas
The three most important things about origins: location, location, location
title The three most important things about origins: location, location, location
title_full The three most important things about origins: location, location, location
title_fullStr The three most important things about origins: location, location, location
title_full_unstemmed The three most important things about origins: location, location, location
title_short The three most important things about origins: location, location, location
title_sort three most important things about origins: location, location, location
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023393/
https://www.ncbi.nlm.nih.gov/pubmed/24705498
http://dx.doi.org/10.1002/msb.145202
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