Cargando…

Calpain: a molecule to induce AIF-mediated necroptosis in RGC-5 following elevated hydrostatic pressure

BACKGROUND: RIP3 (Receptor-interacting protein 3) pathway was mainly described as the molecular mechanism of necroptosis (programmed necrosis). But recently, non-RIP3 pathways were found to mediate necroptosis. We deliberate to investigate the effect of calpain, a molecule to induce necroptosis as r...

Descripción completa

Detalles Bibliográficos
Autores principales: Shang, Lei, Huang, Ju-Fang, Ding, Wei, Chen, Shuang, Xue, Li-Xiang, Ma, Ruo-Fei, Xiong, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023497/
https://www.ncbi.nlm.nih.gov/pubmed/24884644
http://dx.doi.org/10.1186/1471-2202-15-63