Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome

BACKGROUND: To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. MATERIALS AND METHODS: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assess...

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Detalles Bibliográficos
Autores principales: Salehpour, Saghar, Manzor-al-ajdad, Ozra, Samani, Elham Neisani, Abadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023503/
https://www.ncbi.nlm.nih.gov/pubmed/24851177
Descripción
Sumario:BACKGROUND: To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. MATERIALS AND METHODS: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed. RESULTS: The mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women. CONCLUSION: These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.

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