Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome

BACKGROUND: To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. MATERIALS AND METHODS: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assess...

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Autores principales: Salehpour, Saghar, Manzor-al-ajdad, Ozra, Samani, Elham Neisani, Abadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023503/
https://www.ncbi.nlm.nih.gov/pubmed/24851177
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author Salehpour, Saghar
Manzor-al-ajdad, Ozra
Samani, Elham Neisani
Abadi, Alireza
author_facet Salehpour, Saghar
Manzor-al-ajdad, Ozra
Samani, Elham Neisani
Abadi, Alireza
author_sort Salehpour, Saghar
collection PubMed
description BACKGROUND: To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. MATERIALS AND METHODS: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed. RESULTS: The mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women. CONCLUSION: These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.
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spelling pubmed-40235032014-05-21 Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome Salehpour, Saghar Manzor-al-ajdad, Ozra Samani, Elham Neisani Abadi, Alireza Int J Fertil Steril Original Article BACKGROUND: To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. MATERIALS AND METHODS: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed. RESULTS: The mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women. CONCLUSION: These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship. Royan Institute 2011 2011-02-20 /pmc/articles/PMC4023503/ /pubmed/24851177 Text en Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Salehpour, Saghar
Manzor-al-ajdad, Ozra
Samani, Elham Neisani
Abadi, Alireza
Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
title Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
title_full Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
title_fullStr Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
title_full_unstemmed Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
title_short Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
title_sort evaluation of homocysteine levels in patients with polycystic ovarian syndrome
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023503/
https://www.ncbi.nlm.nih.gov/pubmed/24851177
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