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TRPV1 structures in distinct conformations reveal mechanisms of activation
TRP channels are polymodal signal detectors that respond to a wide range of physical and chemical stimuli. Elucidating how these channels integrate and convert physiological signals into channel opening is essential to understanding how they regulate cell excitability under normal and pathophysiolog...
Autores principales: | Cao, Erhu, Liao, Maofu, Cheng, Yifan, Julius, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023639/ https://www.ncbi.nlm.nih.gov/pubmed/24305161 http://dx.doi.org/10.1038/nature12823 |
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