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Levels of active tyrosine kinase receptor determine the tumor response to Zalypsis
BACKGROUND: Zalypsis® is a marine compound in phase II clinical trials for multiple myeloma, cervical and endometrial cancer, and Ewing’s sarcoma. However, the determinants of the response to Zalypsis are not well known. The identification of biomarkers for Zalypsis activity would also contribute to...
Autores principales: | Moneo, Victoria, Serelde, Beatriz G, Blanco-Aparicio, Carmen, Diaz-Uriarte, Ramon, Avilés, Pablo, Santamaría, Gemma, Tercero, Juan C, Cuevas, Carmen, Carnero, Amancio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023704/ https://www.ncbi.nlm.nih.gov/pubmed/24758355 http://dx.doi.org/10.1186/1471-2407-14-281 |
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