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Population Pharmacokinetic Assessment of the Effect of Food on Piperaquine Bioavailability in Patients with Uncomplicated Malaria

Previously published literature reports various impacts of food on the oral bioavailability of piperaquine. The aim of this study was to use a population modeling approach to investigate the impact of concomitant intake of a small amount of food on piperaquine pharmacokinetics. This was an open, ran...

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Detalles Bibliográficos
Autores principales: Tarning, Joel, Lindegardh, Niklas, Lwin, Khin Maung, Annerberg, Anna, Kiricharoen, Lily, Ashley, Elizabeth, White, Nicholas J., Nosten, François, Day, Nicholas P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023753/
https://www.ncbi.nlm.nih.gov/pubmed/24449770
http://dx.doi.org/10.1128/AAC.02318-13

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