VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor

Current therapeutic anti-angiogenic biologics used for the treatment of pathological ocular angiogenesis such as in diabetic retinopathy and wet macular degeneration often lead to detrimental side effects due to their interference with normal blood vessel physiology. In this issue of EMBO Molecular...

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Detalles Bibliográficos
Autores principales: Favara, David M, Harris, Adrian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Closeups
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023881/
https://www.ncbi.nlm.nih.gov/pubmed/24803395
http://dx.doi.org/10.1002/emmm.201404026
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author Favara, David M
Harris, Adrian L
author_facet Favara, David M
Harris, Adrian L
author_sort Favara, David M
collection PubMed
description Current therapeutic anti-angiogenic biologics used for the treatment of pathological ocular angiogenesis such as in diabetic retinopathy and wet macular degeneration often lead to detrimental side effects due to their interference with normal blood vessel physiology. In this issue of EMBO Molecular Medicine, Michael et al report on a novel angiogenesis inhibitor with unique properties that allow for local inhibition of angiogenesis without detectable systemic side effects.
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spelling pubmed-40238812014-05-22 VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor Favara, David M Harris, Adrian L EMBO Mol Med Closeups Current therapeutic anti-angiogenic biologics used for the treatment of pathological ocular angiogenesis such as in diabetic retinopathy and wet macular degeneration often lead to detrimental side effects due to their interference with normal blood vessel physiology. In this issue of EMBO Molecular Medicine, Michael et al report on a novel angiogenesis inhibitor with unique properties that allow for local inhibition of angiogenesis without detectable systemic side effects. BlackWell Publishing Ltd 2014-05 2014-05-06 /pmc/articles/PMC4023881/ /pubmed/24803395 http://dx.doi.org/10.1002/emmm.201404026 Text en © 2014 The Authors. Published under the terms of the CC BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Closeups
Favara, David M
Harris, Adrian L
VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor
title VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor
title_full VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor
title_fullStr VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor
title_full_unstemmed VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor
title_short VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor
title_sort vegf sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor
topic Closeups
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023881/
https://www.ncbi.nlm.nih.gov/pubmed/24803395
http://dx.doi.org/10.1002/emmm.201404026
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