Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing

In the normal quiescent vasculature, only 0.01% of endothelial cells (ECs) are proliferating. However, this proportion increases dramatically following the angiogenic switch during tumor growth or wound healing. Recent evidence suggests that this angiogenic switch is accompanied by a metabolic switc...

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Detalles Bibliográficos
Autores principales: Coutelle, Oliver, Hornig-Do, Hue-Tran, Witt, Axel, Andree, Maria, Schiffmann, Lars M, Piekarek, Michael, Brinkmann, Kerstin, Seeger, Jens M, Liwschitz, Maxim, Miwa, Satomi, Hallek, Michael, Krönke, Martin, Trifunovic, Aleksandra, Eming, Sabine A, Wiesner, Rudolf J, Hacker, Ulrich T, Kashkar, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023885/
https://www.ncbi.nlm.nih.gov/pubmed/24648500
http://dx.doi.org/10.1002/emmm.201303016

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