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Targeting Prolyl Endopeptidase with Valproic Acid as a Potential Modulator of Neutrophilic Inflammation
A novel neutrophil chemoattractant derived from collagen, proline-glycine-proline (PGP), has been recently characterized in chronic obstructive pulmonary disease (COPD). This peptide is derived via the proteolytic activity of matrix metalloproteases (MMP's)-8/9 and PE, enzymes produced by neutr...
Autores principales: | Abdul Roda, Mojtaba, Sadik, Mariam, Gaggar, Amit, Hardison, Matthew T., Jablonsky, Michael J., Braber, Saskia, Blalock, James Edwin, Redegeld, Frank A., Folkerts, Gert, Jackson, Patricia L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023971/ https://www.ncbi.nlm.nih.gov/pubmed/24835793 http://dx.doi.org/10.1371/journal.pone.0097594 |
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