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The Role of the HIF-1α Transcription Factor in Increased Cell Division at Physiological Oxygen Tensions
HIF-1 is a transcription factor that mediates the cellular responses to low oxygen environments, mainly as a result of having an oxygen-labile subunit, HIF-1α. HIF-1α has been carefully studied in the context of severe hypoxic stresses (<1% O(2)), but it is also known to be present at oxygen tens...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024011/ https://www.ncbi.nlm.nih.gov/pubmed/24835245 http://dx.doi.org/10.1371/journal.pone.0097938 |