Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic CD8(+) T Cells

In human tuberculosis (TB), CD8(+) T cells contribute to host defense by the release of Th1 cytokines and the direct killing of Mycobacterium tuberculosis (Mtb)-infected macrophages via granule exocytosis pathway or the engagement of receptors on target cells. Previously we demonstrated that strain...

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Detalles Bibliográficos
Autores principales: Geffner, Laura, Basile, Juan Ignacio, Yokobori, Noemí, Kviatcovsky, Denise, Sabio y García, Carmen, Ritacco, Viviana, López, Beatriz, Sasiain, María del Carmen, de la Barrera, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024032/
https://www.ncbi.nlm.nih.gov/pubmed/24836916
http://dx.doi.org/10.1371/journal.pone.0097837

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