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RNA secondary structure modeling at consistent high accuracy using differential SHAPE

RNA secondary structure modeling is a challenging problem, and recent successes have raised the standards for accuracy, consistency, and tractability. Large increases in accuracy have been achieved by including data on reactivity toward chemical probes: Incorporation of 1M7 SHAPE reactivity data int...

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Detalles Bibliográficos
Autores principales: Rice, Greggory M., Leonard, Christopher W., Weeks, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024639/
https://www.ncbi.nlm.nih.gov/pubmed/24742934
http://dx.doi.org/10.1261/rna.043323.113

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