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The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin
Malaria is caused by a protozoan parasite that replicates within an intraerythrocytic parasitophorous vacuole. Release (egress) of malaria merozoites from the host erythrocyte is a highly regulated and calcium-dependent event that is critical for disease progression. Minutes before egress, an essent...
Autores principales: | Withers-Martinez, Chrislaine, Strath, Malcolm, Hackett, Fiona, Haire, Lesley F., Howell, Steven A., Walker, Philip A., Evangelos, Christodoulou, Dodson, Guy G., Blackman, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024747/ https://www.ncbi.nlm.nih.gov/pubmed/24785947 http://dx.doi.org/10.1038/ncomms4726 |
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