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Probing Chemical Space with Alkaloid-Inspired Libraries

Screening of small molecule libraries is an important aspect of probe and drug discovery science. Numerous authors have suggested that bioactive natural products are attractive starting points for such libraries, due to their structural complexity and sp(3)-rich character. Here, we describe the cons...

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Detalles Bibliográficos
Autores principales: McLeod, Michael C., Singh, Gurpreet, Plampin, James N., Rane, Digamber, Wang, Jenna L., Day, Victor W., Aubé, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024831/
https://www.ncbi.nlm.nih.gov/pubmed/24451589
http://dx.doi.org/10.1038/nchem.1844