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Probing Chemical Space with Alkaloid-Inspired Libraries
Screening of small molecule libraries is an important aspect of probe and drug discovery science. Numerous authors have suggested that bioactive natural products are attractive starting points for such libraries, due to their structural complexity and sp(3)-rich character. Here, we describe the cons...
Autores principales: | McLeod, Michael C., Singh, Gurpreet, Plampin, James N., Rane, Digamber, Wang, Jenna L., Day, Victor W., Aubé, Jeffrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024831/ https://www.ncbi.nlm.nih.gov/pubmed/24451589 http://dx.doi.org/10.1038/nchem.1844 |
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