Methylenetetrahydrofolate Reductase 677 Genotype-Specific Reference Values for Plasma Homocysteine and Serum Folate Concentrations in Korean Population Aged 45 to 74 Years: The Namwon Study

The reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion criteria. For plasma tHcy concentration (µM/L), reference values (median [5-95 perce...

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Detalles Bibliográficos
Autores principales: Kweon, Sun-Seog, Lee, Young-Hoon, Jeong, Seul-Ki, Nam, Hae-Sung, Park, Kyeong-Soo, Choi, Seong-Woo, Kim, Bok-Hee, Kim, Hee Nam, Choi, Jin-Su, Shin, Min-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024951/
https://www.ncbi.nlm.nih.gov/pubmed/24851035
http://dx.doi.org/10.3346/jkms.2014.29.5.743
Descripción
Sumario:The reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion criteria. For plasma tHcy concentration (µM/L), reference values (median [5-95 percentile]) were 7.72 (5.03 to 13.80) and 6.09 (3.95-10.19) in men and women, respectively. For serum folate concentration (nM/L), reference values were 23.71 (11.73-38.44) and 28.95 (15.23-40.44) in men and women, respectively. The tHcy levels of both genders in the present study were lower than those in previous reports from other countries and Korea. GRAPHICAL ABSTRACT: [Image: see text]

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