New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation

New oral anticoagulants (NOAC) have demonstrated their efficacy as an alternative to vitamin K antagonists (VKA) in the prophylaxis of cardioembolic events in patients with atrial fibrillation (AF). However, evidence on the benefits of NOAC in health-related quality of life (HRQoL) is lacking.We eva...

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Autores principales: Alegret, Josep M., Viñolas, Xavier, Arias, Miguel A., Martínez-Rubio, Antoni, Rebollo, Pablo, Ràfols, Carles, Martínez-Sande, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025166/
https://www.ncbi.nlm.nih.gov/pubmed/24843316
http://dx.doi.org/10.7150/ijms.8916
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author Alegret, Josep M.
Viñolas, Xavier
Arias, Miguel A.
Martínez-Rubio, Antoni
Rebollo, Pablo
Ràfols, Carles
Martínez-Sande, José L.
author_facet Alegret, Josep M.
Viñolas, Xavier
Arias, Miguel A.
Martínez-Rubio, Antoni
Rebollo, Pablo
Ràfols, Carles
Martínez-Sande, José L.
author_sort Alegret, Josep M.
collection PubMed
description New oral anticoagulants (NOAC) have demonstrated their efficacy as an alternative to vitamin K antagonists (VKA) in the prophylaxis of cardioembolic events in patients with atrial fibrillation (AF). However, evidence on the benefits of NOAC in health-related quality of life (HRQoL) is lacking.We evaluated changes in HRQoL related to oral anticoagulation therapy employing a specific questionnaire in a cohort of 416 patients with AF undergoing electrical cardioversion. In terms of HRQoL, we observed a progressive adaptation to treatment with VKA; satisfaction with NOAC remained constant. Older age, higher left ventricular ejection fraction and NOAC were associated with better HRQoL.
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spelling pubmed-40251662014-05-19 New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation Alegret, Josep M. Viñolas, Xavier Arias, Miguel A. Martínez-Rubio, Antoni Rebollo, Pablo Ràfols, Carles Martínez-Sande, José L. Int J Med Sci Research Paper New oral anticoagulants (NOAC) have demonstrated their efficacy as an alternative to vitamin K antagonists (VKA) in the prophylaxis of cardioembolic events in patients with atrial fibrillation (AF). However, evidence on the benefits of NOAC in health-related quality of life (HRQoL) is lacking.We evaluated changes in HRQoL related to oral anticoagulation therapy employing a specific questionnaire in a cohort of 416 patients with AF undergoing electrical cardioversion. In terms of HRQoL, we observed a progressive adaptation to treatment with VKA; satisfaction with NOAC remained constant. Older age, higher left ventricular ejection fraction and NOAC were associated with better HRQoL. Ivyspring International Publisher 2014-05-01 /pmc/articles/PMC4025166/ /pubmed/24843316 http://dx.doi.org/10.7150/ijms.8916 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
spellingShingle Research Paper
Alegret, Josep M.
Viñolas, Xavier
Arias, Miguel A.
Martínez-Rubio, Antoni
Rebollo, Pablo
Ràfols, Carles
Martínez-Sande, José L.
New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation
title New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation
title_full New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation
title_fullStr New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation
title_full_unstemmed New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation
title_short New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation
title_sort new oral anticoagulants vs vitamin k antagonists: benefits for health-related quality of life in patients with atrial fibrillation
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025166/
https://www.ncbi.nlm.nih.gov/pubmed/24843316
http://dx.doi.org/10.7150/ijms.8916
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