Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden

BACKGROUND: Current treatment of ovarian cancer patients with chemotherapy leaves behind a residual tumor which results in recurrent ovarian cancer within a short time frame. We have previously demonstrated that a single short-term treatment of ovarian cancer cells with chemotherapy in vitro resulte...

Descripción completa

Detalles Bibliográficos
Autores principales: Abubaker, Khalid, Luwor, Rodney B, Zhu, Hongjian, McNally, Orla, Quinn, Michael A, Burns, Christopher J, Thompson, Erik W, Findlay, Jock K, Ahmed, Nuzhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025194/
https://www.ncbi.nlm.nih.gov/pubmed/24886434
http://dx.doi.org/10.1186/1471-2407-14-317

Ejemplares similares

Ejemplares similares